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Some experiments also confirmed that Prdx6 could moderate lipopolysaccharide (LPS)-induced AKI by decreasing oxidative stress and inflammation[155]

Arginine (Arg), through its metabolism via the inducible nitric oxide synthase (iNOS) and arginase pathways, contributes to immune regulation

2019;27:67380 Demonstrated that systemic injections of cartilage-targeted IGF-1 fusion proteins had direct effects on the growth plate without off-target effects on the kidney that are seen with normal IGF-1