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Description

On ice, cells were scraped and collected in extraction buffer containing methanol:acetonitrile:H 2 O (4:4:2), 15 M glutaric acid and 0.5% formic acid

Analyses were adjusted for relevant demographic, cardiovascular and stroke-related characteristics

The trial evaluated once weekly cagrilintide doses in participants with overweight or obesity and reported dose dependent reductions in body weight at 26 weeks, with the paper describing the treatment as well tolerated in the study setting