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These systems achieve controlled drug release by modulating the physicochemical properties of polymers, such as solubility, release kinetics, and targeting capabilities, thereby enhancing therapeutic efficacy and reducing adverse effects ( 4.3.1 Basic polymeric nanocarrier systems Nanoparticle systems use polymeric nanoparticles as core carriers to effectively encapsulate drugs and deliver them to specific sites (e.g., joints and tumor regions) through passive or active targeting mechanisms (Zhao and Zhou, 2022)

Lots of ingredients used in skincare have a long history of use in medicine

Chemico-biological Interactions 348, 109625

Decreased doses produce less significant increases in growth hormone concentration