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A case-control study of corticosteroid use during the first trimester of pregnancy noted an increased risk of oral clefts in newborns

Patient and sample attributes for the TCGA cohort were downloaded from the GDC data portal (gdc-tcga-phs000178-controlled) using the R package GenomicDataCommons version 1.18.0 and from the supplementary tables publicly available on the PanCanAtlas page ( Only patients included in the BRCA study of TCGA and for which we found no reason for exclusion were considered (Supplementary Fig

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