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They utilized findings from their previous study, where they had performed spatial transcriptomic profiling to define the molecular map of a healing tendon and discovered something momentous: high levels of Acp5 gene expression at the site of a healing tendon

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To test if ferroptosis signaling can induce axonal fusion in mammalian neurons, we applied the ferroptosis inducing agent ML162 to transected and re-sutured mouse sciatic nerves and examined the effect on functional restoration (Fig