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Subcutaneous (SubQ) injection of GHK-Cu outperforms intramuscular (IM) for cosmetic applications because adipose tissue acts as a sustained-release depot, extending plasma half-life by 4060% while maintaining therapeutic copper-peptide concentrations at the dermal layer

It is enriched with phytoestrogens, which are potential reproductive disruptors as previously described in animal models (95, 96)

Even modest weight reduction of 5-7% significantly enhances insulin receptor function in muscle and liver tissue

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