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For comparison, a mammalian cell line tolerated AF at concentration as high as 100 M for 5 d, while 5 M AF led to adult worm death in 24 h (Figure 6B)

Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Variation Analysis (GSVA) analysis revealed significant activation of the glutathione metabolism pathway in drug-resistant breast cancer tissues compared to sensitive tissues after FEC (5-Fluorouracil, Epirubicin, and Cyclophosphamide) + docetaxel treatment (Fig