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With over 180,000 publications indexed in PubMed, glutathione occupies a central position in cellular redox homeostasis, xenobiotic detoxification, immune regulation, and signal transduction

Epigenetics refers to long-lasting changes in gene expression that are regulated by transcriptional, post-transcriptional, intra- or post-translational mechanisms (such as DNA methylation, histone modifications, and microRNA regulation) that do not involve DNA sequence alteration and are usually characterized by stability and longevity [84]

In aging models, it restores youthful gene expression patterns, increasing protective factors and reducing genes associated with inflammation or degeneration