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About 50% of the histamine in the brain is from mast cells.[ref] Diphenhydramine (Benadryl) has the side effect of making people sleepy due to blocking the actions of histamine in the brain

Rather than forcing change, GHK-Cu reminds the body how to repair itself the way it did when we were younger, which is why its gaining attention not just in skincare, but also in regenerative and longevity medicine