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GeroScience 45 , 2943 (2023)

These findings suggest that Schwann cells and other accompanying cells that are crucial in supporting optimized peripheral nerve structure and function and in promoting axonal regeneration after nerve transection [87,88] are potential targets of cortistatin, which could act in an autocrine and/or paracrine manner in this context

the first step involves the reduction of the first molecule of H 2 O 2 accompanied by the formation of oxyferryl species (Fe IV O) and in the course of the second step, the Fe IV O complex is reduced by the second molecule of H 2 O 2 to O 2 , and H 2 O molecules and free enzyme (Lardinois 1995

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