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Production of the mitochondrial intermediate succinate is impaired, and the mitochondrial tricarboxylic acid cycle (TCA) cycle changes direction (29)

It helps the body to make healthy red blood cells, maintain the nervous system, and release energy from food

However, the liposomal treatment resulted in a significant increase in calcium levels compared to baseline at 2 hours, with no differences between treatments

Clinical Trials: Impact of B12 Supplementation on Metabolites Below are four graphs showing the response to B12 supplementation of serum B12, holotranscobalamin, MMA, and homocysteine: Eight trials of predominantly older adults with at least mild deficiency (Dangour, 2015