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Consistently, hippocampal A-injected Wistar rats treated with TQ exhibited improved memory performance in passive avoidance and shuttle box tests, reduced plaque burden in the CA1 region, increased neuronal survival, and prolonged latency times, further supporting the cognitive-enhancing and neurorestorative properties of TQ in the AD pathology [41]

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The pooled fractions (approximate 6 ml) were concentrated (approximate 0.6 ml) (centrifugal tube: Amicon Ultra-4 centrifugal filter unit with 10 kDa cutoff, from Millipore) and followed by 2D crystallization trials

Patients with irregular menstrual bleeding should not use CYKLOKAPRON until the cause of the irregularity has been established