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Organoid lines were developed following established protocols with slight modifications

Peer review Peer review information Nature Chemical Biology thanks Baishan Jiang, Yi Sun and the other, anonymous, reviewers for their contribution to the peer review of this work

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Differential observations suggest that the role of caveolin 1 in hepatic lipid accumulation may differ depending on how the steatosis is induced, e.g., via high fat diet or fasting