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They showed that concomitant inhibition of NRF2 using ML385 and of GPX4 using FIN56 or RSL3 synergistically eradicate AML through ferroptosis and apoptosis induction, suggesting that such a combination of therapy may represent a promising approach for the treatment of AML

doi: 10.3390/jcm12030893 [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Anggraini DR, Feriyawati L, Sitorus MS, Syarifah S, Daulay M