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In experimental models, Ipamorelin activates Gq/PLC-dependent calcium signaling pathways that stimulate growth hormone release while demonstrating minimal activity on other pituitary hormones, including ACTH, prolactin, FSH, LH, TSH, and cortisol

*Correspondence: Hongguang Zhang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers