Pure Synergy Super B-Complex : Another excellent B complex option, this whole-foods-based vitamin contains all eight essential B vitamins, including 200 mcg of vitamin B12
NLRP nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain, NO nitric oxide, NOS NO synthase, NPY neuropeptide Y, Nrf-2 nuclear factor erythroid 2-related factor 2, PGE2 prostaglandin E2, PI3K phosphatidylinositol-3 kinase, PPAR- proliferator-activated receptor , PRR pattern recognition receptor, TGF- transforming growth factor , TLR toll-like receptor, TNF- tumor necrosis factor-, TNFR tumor necrosis factor receptor, TRADD TNFR1 signal transducer, TRAF TNFR-associated factor, VEGF vascular endothelial growth factor, Interleukins IL-1, IL-4, and IL-6 are shown on the neuroinflammation signaling pathways in Figure S1 (in the Supplement), activating many cellular and physiological functions, including both harmful ones such as ROS production, oxidative stress, neuron damage, A generation, BBB disruption, and beneficial defense processes including neuroprotection, microglia activation and survival, post-synaptic neuron apoptosis, neurogenesis, phagocytosis of damaged neurons, microglial proliferation, A clearance, etc
Shannon CE, Nixon AV, et al
iScience 2023;26:107730
