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Description

Abbreviations: RIPK1: receptor-interacting protein kinase 1

The compounds were shown to disrupt KRAS activity by inhibiting guanine nucleotide exchange factor (GEF)-catalyzed nucleotide exchange and blocking effector binding, effectively stabilizing the protein in its inactive state

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These may include: Mild pain at the injection site Redness or swelling Headache Nausea Serious reactions are rare, but healthcare professionals must always be prepared to manage them