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other allergic reactions that have been reported include erythema, skin rash (unspecified), pruritus, general malaise, and respiratory difficulty due to bronchospasm

Symptoms of Heavy Period Bleeding You might be experiencing heavy periods if you notice: Having to change pads or tampons every hour or even more often Passing blood clots bigger than a 10p coin Periods lasting longer than a week Needing to use both a tampon and a pad together Blood soaking through to your clothes or bedding Feeling constantly tired or breathless Dealing with intense period pain or cramping What causes heavy periods and bleeding

It also has not been approved by the European Medicines Agency or any other major health regulator in other countries

The titration exists to give your body time to adjust