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ROS also attack unsaturated fatty acids in cell membranes and lipoproteins, triggering lipid peroxidation that compromises membrane integrity and fluidity [109]

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Cen P, Ajani JA, Correa AM, Lee JH, Maru DM, Anandasabapathy S, Liao Z, Hofstetter WL, Swisher SG , Komaki R, Ross WA

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It stabilizes IkB-alpha, blocks p65 nuclear translocation, and suppresses MAPK activation, effectively turning off the transcriptional program that drives sustained inflammation

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