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[1] Niacinamide in high doses can sometimes cause nausea, heartburn, or a sensation of warmth

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For recovery enhancement, performance optimisation, or longevity goals in healthy people, until a randomised, placebo-controlled trial in a defined population with an objective primary endpoint and pharmacovigilance over a clinically meaningful duration produces data we do not currently have, we just don't have good evidence of benefit, let alone safety