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Its expression is increased in human leukemia cells during ferroptosis due to the activation of transcription factor ATF4 (activating transcription factor 4) [134]

Alcohols diuretic effect causes dehydration and concentrates urine, which is irritating to an inflamed bladder and counterproductive to bacterial flushing

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Moreover, this process stimulates the release of cytokines like IL-17 A, IL-21, NF-B, and TNF-, resulting in elevated levels of chemokines, adhesion molecules, and matrix metalloproteinases (MMP)