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Age-associated differences in activation of Akt/GSK-3beta signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heart

Hypoxia Apart from the sustained hypoxic background existing in the circulatory system of patients with previous CKD, hypoxia results from the damage to adventitia and the dissection of vasa vasorum vessels during the creation of AVF

In addition, IGF-IR has high homology with the closely related insulin receptor (InsR), which has two isoforms, InsR-A and InsR-B [24]

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