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And so thats one of my worries with these peptides, is that theyll kind of encourage moving along the pathway towards an actual cancer. The larger problem is that researchers lack the human data needed to measure either the risk or the claimed benefit

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Larger sample sizes along with functional validation will be needed to further implicate these germline variants in lung cancer pathogenesis, although these early studies in individuals who have never smoked have highlighted the presence of pathogenic alterations with large effect sizes in DNA repair-related genes

The authors declare that they have no competing interests