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Taken together, Akkermansia muciniphila may exert a double-edged sword effect on the homeostasis of the gut-joint axis through changes in its abundance: at moderate levels, it enhances intestinal barrier function and inhibits inflammation, while dysbiosis (either excessive or insufficient abundance) exacerbates the pathological progression of OA by disrupting mucus layer integrity and promoting toxin translocation

Interventions aiming at controlling hyperglycemia are the primary line of treatment for diabetic patients

Related People Related Targets Personalised Nutrition Related Research Groups Maria Traka

The results showed that GHK-Cu binds directly to SIRT1 and forms a protein complex, with the interacting amino acid residues GLU-230 and ASN-226 being identified (Li et al., 2025)