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232 Several studies have demonstrated that loss of function of UBE3A leads to increased ARC expression and subsequently decreases the number of AMPARs, ultimately impairing synaptic plasticity at excitatory synapses

Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation

For newcomers to this drug class, our primer on what a GLP-1 is and how these peptides are described in research gives the vocabulary used throughout