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Mice in the IMQ group developed typical psoriasis-like changes, such as Munro microabscesses in the corneum, hyperkeratosis and parakeratosis in the epidermis, spinous layer thickening, regularly elongated rete ridges, and lymphocytes infiltration in the dermis (Fig

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Bands were detected by Novex ECL Chemiluminescent Substrate Reagent Kit (Invitrogen, WP20005) using an ImageQuant LAS 4000 mini (GE Healthcare)