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They can then increase the dose to 1030 mg daily [118,119], a dose that can cause some side effects, although very rarely, including nausea, dry mouth, dizziness, headache, and heartburn [120]

In a reaction, superoxide anion quickly reacts with NO radical and forms peroxynitrite (OONO ), which directly interacts with CO 2 to form other highly reactive nitroso peroxocarboxylate (ONOOCO 2 ) or peroxynitrous acid (ONOOH)