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Spatial transcriptomics combined with single-cell RNA sequencing identified high expression levels of ferroptosis-related genes, including TFRC, NCO4, and SLC3A2, in granulosa cells of patients with ovarian senescence, while GPX4 expression was notably low (Lin et al., 2023)

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157 On the one hand, a considerable strength of the 2D LC-ICP-MS workflow is to identify the (mis)metalation targets of metallodrugs containing abiological metals, which benefits from a very low signal background, as long as care is taken to stabilize what might be labile metallodrugprotein adducts

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