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Surrogate models (Lysosome/S9) : Due to the low throughput of cell models, lysosomal fractions and liver S9 fractions serve as high-throughput surrogates for screening novel linkers (Table 2)

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Adoption of high-purity glutathione, liposomal formulations, and bio-fermentation technologies is accelerating, driven by technological advancements, regulatory support, and rising consumer awareness

doi: 10.1523/jneurosci.5032-08.2009 218 BabcockTACarlinJM