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J Environ Health Sci Eng 19:483490 Wallace RB, Stratton K, Bonnie RJ (2007) Ending the tobacco problem: a blueprint for the nation

Reported annual medical and productivity losses are larger than previous estimates of $53 billion (7) and $43 billion (2), respectively

A study by the Catholic University of Maule (UCM) in Chile estimates that approximately 5 trillion cigarettes are discarded annually, making them the most prevalent form of human waste globally, with significant environmental repercussions

Participants randomly received an e-cigarette that delivered 36, 8 or 0 mg/mL of nicotine, or a cigarette substitute that contained no tobacco, as an aid in their efforts to reduce their cigarette consumption