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and Morero, R.D., Curr

Examples are benzodiazepam and imipramine

Studies comparing localized versus systemic delivery for other biologics (botulinum toxin, platelet-rich plasma) suggest systemic routes produce more uniform results across larger treatment areas

A comprehensive 2018 analysis by Pickart and Margolina revealed that GHK-Cu modulates the expression of approximately 4,000 human genes representing 31% of all genes analysed