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Furthermore, the stepwise 1% iterative optimization method reveals distinct carbon emission optimization characteristics across different LCZ types, thereby providing robust support for developing region-specific carbon emission reduction strategies

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However, with respect to desensitization, D 3 R but neither D 2 R nor D 4 R, develops desensitization [23, 24], suggesting that different mechanisms could be involved in the desensitization of GPCRs, depending on receptor or cell environment characteristics