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However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)

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Syringes should have measurement markers on the outside of the syringe and be labeled with how much total volume the syringe can hold

A comparative study with famotidine and cimetidine