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56 Smoking also is a risk factor for cerebrovascular diseases, 57,58,59 including stroke, hypertension, and diabetes, suggesting smoking may affect cognition through vascular pathways

Notably, however, treatment of SV-HUC cells with BCEVs resulted in extremely significant increases in the release of monocyte chemotactic protein 1 (MCP-1), and this upregulation was even more pronounced when these urothelial cells were treated with CSE- or MEL-induced BCEVs (Fig

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