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During the early stages of acute pancreatitis, the inflammatory response damages the intestinal barrier, allowing bacteria and endotoxins to enter the blood, triggering an inflammatory storm, sepsis, and even multiple organ failure [92]

9.6 Probiotics in obesity and cardiometabolic health Among the multiple factors driving the modern escalation of obesity, the most prominent are an inherited genetic susceptibility and a sustained energy imbalance, defined by a chronic excess of caloric intake relative to energy expenditure (412)

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