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(2002) Molecular Biology of the Cell | Kennelly J

Therefore, it can be observed that ferroptosis is involved in the occurrence and progression of IIM, and further exploration is needed to elucidate the exact role of ferroptosis in IIM

The study confirmed FOXO4-DRI was effective across senescent cells generated by different methods (irradiation, doxorubicin, and replication stress), and documented that pre-treatment with FOXO4-DRI attenuated the dedifferentiation of chondrocytes during in vitro expansion establishing it as a valuable tool for research into senescent cell biology in cartilage and musculoskeletal models

R.HaendlerB.VierulaM.et al (2001)