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10.1212/WNL.54.6.1265 Neurology 232 MastersC

ChenTLYangHCHungCYOuMHPanYYChengMLet alImpaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism

We have gone into detail about Witch Hazel in cosmetic products here (it's astringent, soothing, antioxidant and antibacterial), but the important part to know about the leaves is that they contain much, much less active components than the bark

However, the internet will have you believe otherwise