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Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition

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While not a direct allergy treatment, epitalon may contribute to immune homeostasis through its effects on circadian rhythm and melatonin, both of which influence allergic responses