Plant Foods that Contain Glutathione While the focus of this review has been on foods and dietary-derived nutrients for the purpose of supporting antioxidant defenses, primarily by increasing glutathione levels and enzymes related to glutathiones activity, it is worthwhile to note that there are several foods that contain the thiol-rich compounds, glutathione, NAC, and cysteine (Table 2)
Mechanistically, GSH-Au NCs likely modulates redox balance by direct ROS scavenging (evidenced by reduced H 2 O 2 , O 2 , MDA, and EL) and transcriptional upregulation of AsA-GSH genes ( SOD , APX , GR , MDHAR , and DHAR ), consistent with Au NP effects [25,26,27]
Glutathione is one of the most powerful antioxidants produced by the body
SP@M increases LC3-mediated autophagy as well as strengthens ubiquitin-mediated proteasomal degradation toward KEAP1, which promotes the expression and nuclear translocation of NRF2