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It is vital for the production of myelin, the protective sheath that surrounds nerve fibres and enables efficient transmission of nerve signals throughout the body

From a methodological point of view our study highlights the need to use a kinetic approach and direct methods for quantification of metallated protein complexes as well as the neccessity for strict control of buffer, ionic strength and pH value during titration with metal-chelating ligands

Pons R, De Vivo DC: Primary and secondary carnitine deficiency syndromes

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