In Part 1, The Mother of All Antioxidants, we explained the importance of maintaining a healthy ratio of reduced-to-oxidized glutathione, presented common illnesses that arise when imbalances are left untreated, explained the benefits of reduced glutathione (GSH), and revealed the risks of self-medicating with over-the-counter GSH supplements
Optimized, or taking too much
developed a novel DON prodrug, HDON, which can selectively activate nitroreductase in hypoxic tumor environments without affecting oxygen-rich normal tissues, showing significant tumor inhibition in the H22 mouse liver cancer model (Zheng et al., 2024)
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