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A meta-analysis of 11 studies in a total of 705 patients with chronic liver disease (seven different types, and one study only in patients with NASH) showed that SAMe improved AST and total bilirubin levels but not ALT levels [53]

In the presence of Moringa oleifera Lam., the peak plasma concentration of amodiaquine decreased by up to 40%, as well as its area under the plasma concentration-time curve which decreased by approximately 11%, leading to a significantly delayed absorption of amodiaquine (Olawoye et al., 2018)

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