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1 Introduction Vitamin B12, or cobalamin, is a water-soluble vitamin, that plays an essential role in cellular metabolism, particularly in DNA synthesis, methylation processes, and mitochondrial functions (Green et al., 2017)

In ex-vivo follicle culture and rodent models, GHK-Cu has been reported to stimulate dermal papilla proliferation, increase follicle diameter, and improve scalp vascularization

Also in kidney, localization of GLP-1 receptor is under investigation, but it is thought to be expressed in vascular smooth muscle cells and immune cells in kidney [43]