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The ensuing mechanistic investigation suggested that the mRNA expressions of GPx1 contributed about ~ 80% and ~ 50% of the total GPx activity in the jejunum and the ileum of wild-type mice

[iv] Challenges Associated With FIH Trials Since these studies represent the first administration of an investigational drug in humans, they are associated with inherent challenges, especially safety

doi: 10.3389/fmicb.2023.1286364 Summary Keywords fungal infections, antifungal resistance, antifungal agents, drug development, drug design Citation Li Y, Liu Y, Jiang Y, Yang Y, Ni W, Zhang W and Tan L (2025) New antifungal strategies and drug development against WHO critical priority fungal pathogens

On the other hand, NHIC, a subtype of bladder pain syndrome (BPS), involves chronic bladder pain, frequent urination, and urgency, but lacks the observable Hunner lesions found in Hunner-type IC (Mostafa et al., 2024)