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Oxidative stress and glutamate excitotoxicity contribute to apoptosis in cerebral venous sinus thrombosis

A recent Phase III clinical trial focused on gout patients who were intolerant or contraindicated to xanthine oxidase inhibitors (XOIs) revealed that lesinurad monotherapy at a dosage of 400 mg led to a significant incidence of elevated serum creatinine

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Colorectal liver metastasis: molecular mechanism and interventional therapy