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The reason for the association of low vitamin B 12 status with Alzheimer's disease is not clear

doi: 10.2337/DB21-0194 84 SinhaSBorcherdingNRenavikarPSCrawfordMPTsalikianETanseyMet al

Lilly submitted an NDA in late 2025

This means any substance that: Is not approved by any governmental regulatory health authority for human therapeutic use (e.g., drugs under pre-clinical or clinical development)