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CPT1A and metabolic diseases Patients with metabolic syndrome, obesity, and type 2 diabetes frequently have non-alcoholic fatty liver disease, hypertriglyceridemia, and other lipid metabolism abnormalities, which can be somewhat improved by increasing CPT1A expression ( CPT1A in vascular diseases Metabolism of endothelial cell depends on FAO to resist oxidative stress in the development of blood vessels, and CPT1A plays a crucial role in this process, offering a new potential target for the treatment of vascular-related diseases (Rohlenova et al., 2018)

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Recent studies showed that CPT1C was localized both in the endoplasmic reticulum and mitochondria, but its presence in endoplasmic reticulum is predominant