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Bicyclol can change the expression of Mdr-1 , GSH/GST and Bcl-2 , increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs

Based on these comprehensive research findings, we speculate that the regulation of the T1D immune system and inflammatory pathways may be closely linked to butyrate, a key metabolite produced by Clostridium

These results suggest that the presence of TgAb and/or TPOAb at baseline is a common risk factor for pembrolizumab- as well as nivolumab-induced thyroid dysfunction

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