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Microscopy From rats, at end of the experiment, the brain, liver, kidney, stomach, duodenum, jejunum, colon, rectum, lungs, and heart were fixed in 10% neutral buffered formalin (pH 7.4) at room temperature for 24 h

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This multifaceted mechanism, targeting both central appetite centers and peripheral glucose control points, makes it a subject of significant interest in metabolic research

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However, complete symptom resolution, particularly for neurological complications, may take several weeks to months depending on the severity and duration of deficiency before treatment

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