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Obesity is recognized as a chronic inflammatory state characterized by elevated circulating inflammatory cytokines, adipose tissue macrophage infiltration, and systemic low-grade inflammation

Mechanistically, a 2026 PubMed review points to angiogenesis, collagen synthesis, fibroblast activity, and nitric oxide modulation as the likely pathways

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In general, the procedure is performed by first making a small incision in the natural crease under the chin, which allows the doctor to remove any excess fat above the muscle